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I came across an interesting article on the Medical News Today website referencing a paper published in the Science Translational Medicine journal which suggests that NAC- N-Acetyl Cysteine may be an effective treatment modality for osteoarthritis.

The authors suggest that they expect that osteoarthritis is a multi-factorial process and the mechanism of action that they have identified may not provide a total solution to the osteoarthritis process however this article/paper may present us with a new treatment modality to deal with this health issue.

Most health care practitioners would agree that trying to treat osteoarthritis simply by consuming nutritional supplements is short sighted and this approach does not take into consideration a functional approach such as looking at factors like diet (inflammatory vs. anti-inflammatory), gut health, toxins etc.

Let’s quickly review some of the benefits of NAC:

Health Benefits of Time Restricted Feeding

It is interesting to reflect on some of the significant dietary trends which have gained some traction in the general population during the past several years: I would suggest that the key movements have included the Paleo movement which has to an extent transitioned now into the LCHF (Low Carb / High Fat) / Keto movement, vegetarian and vegan, fasting and intermittent fasting – and most recently Time Restricted Feeding (TRF).

Although there is to date not a lot of published research on the topic of TRF, it is becoming a topic of significant discussion amongst the LCHF / Keto practitioner community.

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Today I want to share with you an intriguing article and the related abstract which hypothesizes that ALCAR – Acetyl-L-Carnitine may provide an inexpensive and fast acting intervention for depression.

I am sure that most who read this newsletter are familiar with ALCAR – it is an acetylated form of L-Carnitine which is endogenously produced.

Here is a quick bullet point review of some of the key benefits of ALCAR from the Self-Hacked website:

The Health Benefits of Carnitine

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The hormone Melatonin is best known for its impact on sleep and circadian rhythms, however it provides many additional health benefits.

The published paper I want to share with you today refers to its potential benefits for individuals who deal with Type ll Diabetes with CHD: but also it cautions about a common gene variant (30 % of the population) in which typical Melatonin dosages may create problems.

Here are a couple of highlights from the paper:

CONCLUSIONS: Overall, melatonin intake for 12 weeks to diabetic patients with CHD had beneficial effects on plasma GSH, NO, MDA, PCO, serum hs-CRP levels, glycemic control, HDL-cholesterol, total-/HDL-cholesterol ratio, blood pressures and parameters of mental health.

 And 6 Key Takeaways:

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This newsletter article is longer than I usually write, however I believe that the content is important enough that it warrants this consideration.

This week I listened to a riveting podcast on Evan Brand’s website. Evan is a Functional Medicine Practitioner and he hosts some great podcasts.

The topic was glyphosate, which as I am sure most will know is a key ingredient in the Monsanto weed killer product Roundup, the most widely used herbicide in the world.

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Following is an article from the Natural Medicine Journal: the journal of the American Naturopathic Association which provides an excellent review of the many clinical applications of Low Dose Naltrexone (LDN)

Reviewed applications include the following:

  • Anti-inflammatory activity
  • Regulation of the opioid growth factor
  • Autoimmune Conditions
  • Cancer
  • Depression
  • Dissociative Disorders and Post-Traumatic Stress Syndrome

As suggested in this review, LDN can provide an excellent therapeutic option for some of the health issues described.

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