Category: Cardiovascular Health

Pricera NAD+ Precursor – Healthy Aging

Written by Rob on . Posted in Anti-aging, Blood Sugar, Brain Health / Conditions, Cardiovascular Health, Disease Conditions, Health News, Pain / Inflammation, Sexual Health. Leave a Comment

I want to share with you a podcast I recently guested on that really goes into the science of NAD+, ENERGY and the benefits of Pricera – here is the link: https://lnkd.in/g-EK96G

Here is some  information on our NAD+ precursor formulation – Pricera.

– NAD+ levels decline precipitously as we age: it is down 50% by the age of 50 and down 90 – 96% by the age of 80
– one of the key functions of NAD+ is to activate the Sirtuin longevity genes which are critical for healthy aging
– when the Sirtuins are not activated, it accelerates vascular aging which will of course impact on the vascular system  but since the vascular system delivers oxygen and nutrients to every cell in the body, the lack of NAD+ will have a consequential negative impact on virtually EVERY cell in the body and virtually all chronic degenerative conditions

Increased Energy Levels

Certainly reported increased energy (due to Pricera’s impact on the mitochondria) has been widely reported however that is just one reported benefit – and the report often comes in from individuals in good to excellent health.

Others key applications include:

  • Neurodegenerative conditions – such as Parkinson’s
  • Inflammation
  • Addictions
  • Chronic Fatigue Syndrome
  • Exercise performance and recovery
  • Immune system activation
  • Low energy/mitochondrial dysfunctions
  • Blood sugar issues
  • Hypertension
  • Elevated cholesterol levels
  • Mood disorders
  • Oxidative stress

Order Pricera now:

http://www.healthspan-formulations.com

Here are a couple of examples of typical testimonials:

Liking Pricera 🙂

Definitely boosting energy and focus.
It’s been ages since I got out in the evening for a bike ride
just because I was so knackered.

This changed within 2 days of starting the Pricera.
Also more mental clarity.

Chris Spooner, ND
Vernon, BC 

For a number of years I have been dealing with low energy and stamina, Chronic Fatigue and hand tremors. 

One of the key areas where Pricera impacts me is my energy levels – in the past, I often could only work for 4-5 hours before I felt exhausted and would have to stop. 

Some days it felt like my energy levels were so depleted that it was a struggle to get out of bed. 

Since starting on the Pricera, I have experienced a tremendous boost to my energy levels and I can now work 8-10 hours at a stretch. 

I have gained more stamina, energy and clarity and I have seen a significant improvement in my exercise capacity. 

For myself, Pricera has been a life saver, and I will not miss a single day taking it! 

Let me know if you would like any additional information or if you have any questions.

http://www.healthspan-formulations.com

Raised Blood Pressure at Any Age Speeds Cognitive Decline

Written by Rob on . Posted in Anti-aging, Brain Health / Conditions, Cardiovascular Health, Disease Conditions, Health News. Leave a Comment

I wanted to share with you an article from Fight Aging!
on the topic of hypertension and cognitive decline.

Fight Aging! puts out a free weekly newsletter on current developments in the area of aging research – I have been subscribing to it for many years.

Regards,

Rob

Here is a reminder that the increased blood pressure of hypertension, or even more modestly raised blood pressure, is an important downstream mechanism in aging. Higher blood pressure over time results in greater tissue damage to the brain, kidneys, and other organs, greater vulnerability to atherosclerosis, and many more issues. Raised blood pressure is one of the more important ways in which the underlying molecular damage of aging is converted into structural and physical damage that leads to death.

High blood pressure appears to accelerate a decline in cognitive performance in middle-aged and older adults. Nearly half of American adults have high blood pressure or hypertension. Having high blood pressure is a risk factor for cognitive decline, which includes such things as memory, verbal fluency, attention and concentration. Blood pressure of 120 mmHg – 129 mmHg systolic (the top number in a reading) or higher is considered elevated. Systolic pressure above 130 mmHg, or diastolic pressure (the bottom number) of 80 mmHg or higher is considered hypertension.

Researchers analyzed findings from an existing study that included blood pressure and cognitive health information for more than 7,000 adults in Brazil, whose average age was about 59 years old at the study’s start. The study participants were followed for an average of nearly 4 years; testing included analysis of memory, verbal fluency, and executive function, which includes attention, concentration, and other factors associated with thinking and reasoning.

Systolic blood pressure between 121 and 139 mmHg or diastolic blood pressure between 81 and 89 mmHg with no antihypertensive medication use was associated with accelerated cognitive performance decline among middle-aged and older individuals. The speed of decline in cognition happened regardless of hypertension duration, meaning high blood pressure for any length of time, even a short duration, might impact a person’s speed of cognitive decline. Adults with uncontrolled hypertension tended to experience notably faster declines in memory and global cognitive function than adults who had controlled hypertension.

“In addition to other proven benefits of blood pressure control, our results highlight the importance of diagnosing and controlling hypertension in patients of any age to prevent or slow down cognitive decline. Our results also reinforce the need to maintain lower blood pressure levels throughout life, since even prehypertension levels were associated with cognitive decline.”

Link: https://newsroom.heart.org/news/high-blood-pressure-at-any-age-no-matter-how-long-you-have-it-may-speed-cognitive-decline

NOW AVAILABLE: Practitioner grade formulations for blood sugar/diabetes, NAD+ optimization, healthy aging:

https://www.healthspan-formulations.com/

Blood Sugar Support

Written by Rob on . Posted in Anti-aging, Blood Sugar, Brain Health / Conditions, Cardiovascular Health, Diet, Digestion / Gut Health, Disease Conditions, Health News, Sexual Health, Vitamins, Minerals, Herbs. Leave a Comment

Our Blood Sugar Support formulation is now available!

It includes InnoSlim® a stimulant-free, 100% plant-based ingredient to support healthy weight and glucose metabolism.

InnoSlim® has been shown in clinical trials to enhance fat burning, decrease glucose absorption and enhance metabolic wellness

CLINICAL FINDINGS

Supports healthy weight management*

Supports enhanced fat burning and weight loss*

Decreases circulating glucose (in pre-clinicals)*

Supports healthy insulin sensitivity*

Formulated to:

Support normal blood sugar and insulin levels*

Maintain healthy cholesterol and triglyceride levels already within the normal range*

Support cardiovascular wellness*

Decrease sugar cravings*

Appetite suppression*

Block carbs blocking by inhibiting an enzyme that digests sucrose and starch-derived sugar*

Support healthy blood pressure & circulation*

Maintain blood pressure levels that are already within the normal range*

Support healthy brain function*

Provide antioxidant properties*

Promote a healthy inflammatory response*

Enhance AMPK activity+*

And many others


+ AMPK is an enzyme found in every single cell in our bodies where it functions as a “master regulator” switch for energy production. It also plays a critical role in regulating growth

Ingredients

InnoSlim

Berberine HCl.

Alpha Lipoic Acid

Bitter Melon – 10% Charantins

Gymnema sylvestre – 75 % Gymnemic Acid

Pata de Vaca

Mulberry – 1-Deoxynojirimycin HCl (DNJ) 1%

Chromium Picolinate

Each bottle contains 90 capsules: the recommended dose is one capsule per meal 

For more info or to purchase:

Healthspan Formulations

***Not available in Canada

How I Reverse My Biological Age by 15 Years With Supplements

Written by Rob on . Posted in Anti-aging, Blood Sugar, Brain Health / Conditions, Cardiovascular Health, Digestion / Gut Health, Disease Conditions, Female Conditions / Issues, Health News, Male Conditions / Issues, Pain / Inflammation, Sexual Health, Vitamins, Minerals, Herbs. Leave a Comment

Like many of you, I am constantly tinkering and experimenting with different modifiable lifestyle factors to try to optimize my quality of life – I am truly a biohacker.

As you would know, there is a big difference between Chronological Age and Biological Age.  We have all worked with patients and seen individuals who look a lot older – or younger than their Chronological Age.

There are a lot of factors that can influence this difference: we cannot discount genetics however as we all know epigenetic expression can be significantly influenced by lifestyle and environmental factors.

So factors that we typically help our patients with would be included, such as diet, sleep, exercise, mental attitude, exposure to environmental toxins etc. can influence Biological Age.

When I am working with clients, I use a technology device which I have referred to previously – the iHeart technology which functions as a pulse oximeter but as well it measures AoPWV- Aortic Pulse Wave Velocity which is a measurement of aortic flexibility.

This biomarker is increasingly being used by progressive cardiologists and other health care practitioners as an indication of CV health and the potential for future events including sudden death, strokes and heart attacks. 

This is considered a more accurate predictor of these events vs. lipid panels due to the fact that approximately 40% of individuals who have one of these events have normal lipid panels.

But what I really love about the iHeart is that it has an algorithm which compares Chronological Age vs. Biological Age.

I use this technology with all my clients and I find it works well to convey the concept of Healthspan and to optimize compliance.

I use this device regularly on myself and I get good results: I am 66 years old and my Biological Age result is typically around 25 years of age.

I take a lot of supplements and I have been doing some experimentation recently whereby I would check my Biological Age before and after taking my supplements to see if they were having any impact on my Biological Age results.

And sure enough, recent experimentation has shown that prior to taking my supplements my Biological Age reading was around 40 years – and then an hour or two after taking my supplements it was down to around 25 years of age.

And then I wanted to see if I could determine which of my supplements was having the most significant effect.

Sure enough the most significant impact came from just two supplements which would decrease my Biological Age by approximately 15 years and these two supplements turned out to be our two key Integra Nutrition formulations: Pricera, our very popular NAD+ precursor formulation as well as our GenZogenol formulation.

I won’t go into detail on these two formulations in this article: if you want more details on them, have a look at our Integra Nutrition website.

GenZogenol: this formulation includes a key ingredient – Enzogenol which has been shown in a rat study to LENGTHEN telomeres by 40% and in a mouse study to to lengthen healthspan and lifespan by the equivalent of approximately 15 years in humans.

Pricera: is an NAD+ precursor formulation and according to the published literature the best on the market.***

NAD+ levels decrease by 50% by the age of 50 and they are down by 90-96% by the age of 80.

One key factor about NAD+ is it is necessary to activate the Sirtuin longevity genes so if these are not being activated, it accelerates vascular aging which has an impact on virtually every cell in the body.

Optimizing NAD+ levels can have a significant impact on energy levels due to its impact on mitochondrial function: many users feel a surge in energy levels even within 24-72 hours.

These two formulations can have a dramatic positive impact on your personal aging process and healthsplan.

In addition, they can have a significant positive impact on pretty much all chronic, degenerative conditions.

If you would like to get some additional documentation of these two formulations – including some of the published research, reach out to me.

Pricera Testimonials

Liking Pricera 🙂

Definitely boosting energy and focus.
It’s been ages since I got out in the evening for a bike ride just because I was so knackered.

This changed within 2 days of starting the Pricera.
Also more mental clarity.

Chris Spooner, ND
Vernon, BC

For a number of years I have been dealing with low energy and stamina, Chronic Fatigue and hand tremors.

One of the key areas where Pricera impacts me is my energy levels – in the past, I often could only work for 4-5 hours before I felt exhausted and would have to stop.

Some days it felt like my energy levels were so depleted that it was a struggle to get out of bed.

Since starting on the Pricera, I have experienced a tremendous boost to my energy levels and I can now work 8-10 hours at a stretch.

I have gained more stamina, energy and clarity and I have seen a significant improvement in my exercise capacity.

For myself, Pricera has been a life saver, and I will not miss a single day taking it!

MG Vancouver, BC

Why Sleep Deprivation Kills

Written by Rob on . Posted in Anti-aging, Brain Health / Conditions, Cardiovascular Health, Digestion / Gut Health, Disease Conditions, Health News, Pain / Inflammation. Leave a Comment

I wanted to share with you today an article from Quanta magazine which focuses on “Why Sleep Deprivation Kills”.

We all know about the importance of sleep as an integral component of overall health.

We have all experienced the negative effects of a lack of sleep on our health and cognitive function.

Despite decades of research, sleep is still a poorly understood process and why a lack of sleep can cause such significant negative health effects.

Now it appears that part of the answer to this question may have finally been resolved.

As it suggests in the article, many of us would assume that the origin of these types of issues would be focused in the brain however it turns out that this may not in fact be the case, but rather due to the generation of ROS (Reactive Oxygen Species) in the gut.

It is a bit of a long article so here are the abstract as well as study highlights.

If you want to read the whole article you can click on the link above.

Feeling dead tired? Scientists may finally be on the verge of learning why too little sleep is inevitably fatal.
  Article| Volume 181, ISSUE 6, P1307-1328.e15, June 11, 2020

Sleep Loss Can Cause Death through Accumulation of Reactive Oxygen Species
in the Gut

Published:June 04, 2020DOI:
https://doi.org/10.1016/j.cell.2020.04.049

Highlights

  • Sleep deprivation leads to ROS accumulation in the fly and mouse gut
  • Gut-accumulated ROS trigger oxidative stress in this organ
  • Preventing ROS accumulation in the gut allows survival without sleep in flies

Summary

The view that sleep is essential for survival is supported by the ubiquity of this behavior, the apparent existence of sleep-like states in the earliest animals, and the fact that severe sleep loss can be lethal. The cause of this lethality is unknown.

Here we show, using flies and mice, that sleep deprivation leads to accumulation of reactive oxygen species (ROS) and consequent oxidative stress, specifically in the gut. ROS are not just correlates of sleep deprivation but drivers of death: their neutralization prevents oxidative stress and allows flies to have a normal lifespan with little to no sleep.

The rescue can be achieved with oral antioxidant compounds or with gut-targeted transgenic expression of antioxidant enzymes. We conclude that death upon severe sleep restriction can be caused by oxidative stress, that the gut is central in this process, and that survival without sleep is possible when ROS accumulation is prevented.

Pricera is now available!

PRICERA NAD+ Presursor:

KEY APPLICATIONS

  • Parkinson’s and other neurodegenerative conditions
  • Inflammation
  • Addictions
  • Chronic Fatigue Syndrome
  • Exercise performance and recovery
  • Immune system activation
  • Mitochondrial dysfunction
  • Diabesity Spectrum
  • Hypertension
  • Elevated cholesterol levels
  • Depression
  • Oxidative stress

How to Optimize ATP Levels & Mitochondrial Function

Written by Rob on . Posted in Anti-aging, Blood Sugar, Brain Health / Conditions, Cardiovascular Health, Diet, Digestion / Gut Health, Disease Conditions, Health News, Vitamins, Minerals, Herbs. Leave a Comment

Compromised mitochondrial function and the resultant deficit in ATP production is rampant in modern society.

Sub-optimal levels of these conditions are also rampant – often in individuals who would appear to be in a state of good to excellent health.

There are of course many reasons for this state of affairs: age related decline is a given but other stressors such as environmental toxins (including not only chemicals and heavy metals but also factors such as EMF radiation, exposure to blue light, disrupted circadian rhythms, diet, lack of exercise etc.), stress, hormonal dysregulation, and many more.

I would suggest that there is another cause to this challenge: deteriorating age related NAD+ levels.

This latter consideration of sub-optimal mitochondrial function has been something we were not expecting as we have started to get feedback from many practitioners who have been personally consuming our Pricera NAD+ precursor formulation.

Many of these individuals are in apparent good to excellent states of health however within 24-72 hours of starting on Pricera they felt a surge of energy (Pricera’s impact on mitochondrial function), they felt an urge to engage in strenuous exercise, they did so, recovered quickly and felt motivated to engage in exercise again.

An article from the Alive by Nature website discusses a recently published study in Cell Reports in which Jing and co-authors utilized a library of 2,400 drugs to screen for drugs that could restore ATP levels. They successfully identified 15 drugs, influencing a variety of metabolic processes, which significantly increased ATP levels.

Of these, the strongest impact on the production of ATP was NAD+.

The researchers demonstrated that NAD+ activates a transcription cascade that results in

increased expression of mitochondrial proteins involved in ATP production.

I have included the highlights and abstract from Jing’s study at the end of this article.

Jing’s study contributes to a growing body of published research confirming the fact that optimal NAD+ levels are critical for mitochondrial function.

Read More