Category: Cardiovascular Health

Today I want to share with you an article which appeared today in the weekly Fight Aging newsletter.

The Fight Aging newsletter is free and is published and sent out weekly on Sundays.

It is the best source I know of as a summary of current developments in the area of aging research.

This article discusses the concept that age-related degeneration of joints – specifically cartilage is associated with inflammation, which I am sure for most of you is a well known basic concept.

It mentions two key concepts: the Inflammasome as well as Cellular Senescence.

If you are not familiar with the concept of the Inflammasome I have included a link and abstract from a paper published in Nature at the end of this article.

Regarding cellular senescence, I have previously written an article on this topic in October of last year –

Here is a link to the article if you want to review it.

Cellular senescence has been identified as a key factor contributing to the aging process, and it is a key target for both big Pharma as well as Biotech companies to develop compounds which target and destroy senescent cells – referred to as “Senolytics”.

There are currently human drug trials being conducted with senolytic compounds to target senesecent cells (sometimes referred to as “zombie cells” in the common literature) and  I am of the opinion that awareness of this concept will be well established within the general population within probably 12 – 24 months – and I don’t think there is any doubt that health care practitioners across the spectrum will be utilizing senolytic compounds in their practice to target age related degenerative conditions.

Our Activity Relating to Senolytics

I have been extensively researching this topic of cellular senescence and senolytic compounds for approximately two years now and our company is in the final stages of application preparation for an NPN for a natural source senolytic formulation,
so hopefully within about six months or so we will have our formulation approved such that we can bring it to the market:

I will provide you with further information on this topic as we progress towards our product launch.

To my knowledge, at this stage there are no specific natural compound formulations which target cellular senescence – anywhere in the world.

Following is the article: one key takeaway from this article and additional reading I have done on this topic is that senolytic compounds may provide a key approach to arthritic conditions.

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The Dangers of Drinking Sodas

Great article from Organic Lifestyle Magazine on the dangers of drinking soda drinks:

“Soda is proven to be addictive and consumption has been clinically linked to increased blood pressure, high blood sugar, weight gain, kidney disease, heart disease, diabetes, depression, asthma, headaches, ear infections, joint and muscle problems, developmental delays, ADHD, heavy metal toxicity, yeast infections, urinary tract infections, candidiasis, other increased pathogenic activity, increased PMS symptoms, brain damage, liver toxicity, tooth decay, acne, mood swings, decreased fertility in men and women, and so much more!

In other words, drinking soda feeds infections, disrupts the gut microbiome and the metabolic processes, degrades cells, causes chronic illness, exacerbates virtually all chronic illness symptoms, and rapidly ages the body.”

Read More:

https://www.organiclifestylemagazine.com/if-you-drink-soda-its-probably-the-worst-thing-you-do-to-yourself-even-worse-than-smoking

I have determined through my own personal biohacking experimentation that a ketogenic diet is an optimal diet for my metabolism.

In fact what most people refer to as a ketogenic diet is more appropriately described as a modified Atkins diet as a strict ketogenic diet, such as that which is used for children with uncontrolled seizures typically consists of a diet which is composed of approximately 80% fat content which would be very difficult for the average person to follow.

The key to the metabolic benefits of ketosis is developing a state of metabolic flexibility such that the metabolism can switch back and forth effortlessly between burning fat (ketone bodies) and sugar – rather than getting hung up on the depth of ketosis.

And I am not fanatical about staying in ketosis – again the key is being able to effortlessly shift back and forth between burning fat and sugar.

One breakfast meal I will occasionally consume – which is certainly not ketogenic consists of organic berries (I will not consume non organic berries as they are one of the most extensively sprayed foods) with some organic yogurt topped with some seeds and nuts (pumpkin, sunflower, hemp hearts etc.) with a little drizzle of oil on top (typically avocado oil) – and a touch of nut milk.

To this meal I will ALWAYS add some pomegranate – and this is the topic of today’s newsletter.

Pomegranate provides many health benefits – listed below however what I wanted to focus on in this article is the substantial cardiovascular benefits provided by pomegranate.

Following is an article from the Green Med Info website, as well as the abstract from the referred to study.

Here is an outline of some of the various health benefits of pomegranate from an article on the Stylecraze website:

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One of the most dramatic and effective therapeutic modalities for targeting a spectrum of chronic, degenerative diseases – as well as potentially having a direct impact on quality of life/healthspan is now starting to gain some traction in North America.

Used for many years as a therapeutic intervention for serious health issues by the medical community in countries such as Japan, hydrogen therapy is now starting to gain attention in the naturopathic/integrative and functional medicine communities.

Just this past week I was contacted by two local clinics here in Vancouver inquiring about whether I had knowledge about H2 therapy (I do) – and whether I knew where to access a new patent pending H2 tablet product which is becoming very widely used in the U.S. (I do know the contacts for accessing this product).

Six months ago I had the good fortune to meet with one of the co-inventors of this new patent pending tablet technology, to learn more about the product and the research behind it – and as well I have been personally taking the product for some six months now.

So as I do with many interesting therapeutic modalities which may have an impact on disease processes and health, I took a deep dive into the literature to understand more about H2 therapy – and the published research is very impressive:

Why You Should Know About H2 Therapy – and Why You Should Consider Prescribing It To Your Patients
Here is a summary and some links to further published articles on H2 therapy if you have an interest in investigating it further:

From an article from the website H2fx.com:

Research shows molecular hydrogen has the potential to exhibits these effects:

  • Anti-Inflammatory Effects 13
  • Smallest, most bioavailable molecule in existence 14
  • Selective antioxidant 15
  • Participates in Gene Expression 16
  • Anti-Allergic Effects 17
  • Anti-Cellular Death 18
  • Anti-Aging 19
  • Reduces aches and pains 20
  • Protective to skin 21
  • Cardioprotective 22
  • Increases Metabolism 23
  • Increases Body’s Antioxidants (Nrf2 activator) 24
  • Decreases Muscle Fatigue 25
  • Reduces Lactate Levels 26
  • Anti-Diabetic Effects (type 1 and 2) Type 1, 27 Type 2, 28
  • Anticancer 29
  • Improves Cognitive Function 30
  • Protects DNA & RNA 31
  • Anti-Tumor Effects 32
  • Cytotoxic Protection 33
  • Neuroprotective 34
  • Radiation Protection 35
  • With zero toxic effects 36

Based on scientific studies/evidence, hydrogen gas therapy has the potential to benefit:

Alzheimer’s 37, arthritis 38, rheumatoid arthritis 39, Type 1 diabetes 40, Type 2 diabetes 41, Parkinson’s 42, COPD 43, asthma 44, heart disease 45, kidney disease 46, stroke 47, cancer 48, tumors 49, ALS 50, dementia 51, psoriasis 52, dermatitis 53, IBS 54, hemorrhagic shock 55, Crohn’s 56, fatty liver disease 57, liver cirrhosis 58, pancreatitis 59, cardiac arrest 60, neuropathy 61, Multiple Sclerosis 62, Hepatitis B 63, atherosclerosis 64, cataracts 65, hypertension 66, gum disease 67, traumatic brain injury 68, sepsis 69, subarachnoid hemorrhage (aneurysms) 70, infant lung disease 71, metabolic syndrome 72, lymphoma 73, retinitis 74, painful bladder syndrome 75, osteosclerosis 76, osteoarthritis 77, osteoporosis 78, glaucoma 79, pulmonary hypertension 80, pulmonary fibrosis 81, autism 82, depression 83, bipolar disorder 84, anxiety 85, schizophrenia 86, inflammation 87, muscle fatigue 88, increased ATP production 89, soft tissue injuries 90, pain 91, wounds 92, burns 93, seasonal allergies 94, autoimmune disorders 95, insulin resistance 96, hearing loss 97, ulcers 98, radiation damage 99, sleep apnea 100to name just a few as there are studies on over 170 human disease models

If you have an interest in finding out how you can access the H2 tablet product for yourself and/or your patients, reach out to me as I am working directly with the company to make this exciting product available to health care practitioners.

In the near future – within the next five years or so there will be a paradigm shift in how health care practitioners across the spectrum – including allopathic MD’s will be able to help their patients mitigate one of the key identified degenerative processes associated with aging.

What I am referring to is the pending availability of compounds referred to as “senolytics” – compounds developed to target senescent cells (referred to as “zombie cells” in the popular literature).

I suggest that the allopathic MD community will be very much involved in this treatment modality due to the fact that big pharma and the biotech industry are actively engaged in the development of pharmaceutical, prescription drugs for this application.  In fact there are currently trials going on which are testing senolytic drugs and early results should be available later this year.

So let me give you some background and context on why this concept of senolytic compounds is perceived to be such a significant development to target the deterioration associated with the aging process:

Senescent Cells: What Are They?

From the FightAging.org website:

(great free weekly newsletter on the latest developments in the antiaging research community)
The evidence of the past decades, and particularly the past seven years, strongly supports the idea that the accumulation of senescent cells is a root cause of aging. Cells become senescent in large numbers day in and day out, a normal end of life state for somatic cells that have reached the Hayflick limit. Cells also become senescent as the result of damage, or a toxic environment, and there is ever more of that with advancing age. Near all of these cells are destroyed quite quickly after they enter a senescent state, but enough linger to ensure that a few percent of all cells are senescent in old age. These problem cells secrete a potent mix of signals that induces chronic inflammation, degrades tissue structure, and alters the behavior of normal cells for the worse.

Read More…

Image from Dr. Axe website

I was delighted  to see an article published on the Natural News website detailing a study which led research scientists to issue warnings concerning the negative health effects related to the consumption of canola oil.

Many health care practitioners are aware of this, and the fact that canola oil should be considered as one of the commonly available oils which include other oils such as corn, cotton etc. which can cause negative health consequences.

I sometimes look when I am shopping at our local Whole Foods or Choices markets (a similar B.C. based company) for salad dressings which might be made with healthy ingredients, but alas they typically feature which is the top ingredient canola oil.

And the labeling can be deceptive to the average consumer with proud announcements of the product’s organic ingredients – plus the fact that the oil is not cold pressed which means it is produced under conditions of high heat and pressure which makes it unhealthy.

This deceptive advertising reminds me of other deceptive product descriptions such as can be seen in the paleo/keto products available on the market.

This is an issue we need to educate our patients about – and the general public about!  Please feel free to pass this article along, or use it in your discussions/presentations to patients/the general public.

Following is the article from Natural News.

Regards,

Robert (Rob) Lamberton

Scientists finally issue warning against canola oil: Study reveals it is detrimental to brain health, contributes to dementia, causes weight gain

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